We don't ask you to trust the label. We ask you to read the research.
Every ingredient in Activae was selected based on peer-reviewed clinical evidence. Transparency isn't a buzzword — it's our clinical standard.
The absorption advantage.
Nutrient bioavailability is the difference between biological impact and wasted dosage. We prioritize cellular uptake above all.
Compound No. 01
R-Alpha Lipoic Acid
"Superior Nerve Protection"
ALA improved nerve blood flow and conduction velocity through antioxidant-mediated mechanisms.
ALA demonstrated improvement in nerve blood flow through antioxidant-mediated mechanisms in clinical settings.
Oral ALA reduced oxidative stress and improved microcirculation in patients with diabetic peripheral neuropathy.
Compound No. 02
Benfotiamine
"Enhanced Metabolic Support"
Significant improvement in neuropathy symptom score at 6 weeks in a Phase III randomized controlled trial.
Significant neuropathy score improvement vs. placebo in diabetic polyneuropathy.
12-month RCT examining benfotiamine's effects on nerve fiber regeneration and neurophysiological measures.
Complex No. 03
B6 / B12 / Methylfolate
"Neural Signaling Repair"
Comprehensive review of B-vitamin roles in nerve regeneration, myelin maintenance, and neurotransmitter synthesis.
Vitamin B12 promotes axon growth and nerve repair, improving functional neurological recovery.
L-methylfolate combinations show consistent improvements in nerve conduction, fiber density, and neuropathy symptoms across 3,015 patients.
Compound No. 04
Black Pepper Extract
"Formula-Wide Potency Boost"
Reviews BioPerine® as a bioavailability enhancer for nutrients including vitamins and minerals.
Patent documenting the use of piperine to enhance the bioavailability of Vitamin B12 and other nutrients.
How we select ingredients.
Peer-reviewed evidence only
Every molecule must have a body of human clinical trials backing its efficacy for nerve health. No theoretical mechanisms. No animal-only data when human data exists.
Bioavailable forms or nothing
If a more absorbable form exists, we use it. Methylated B-vitamins. Stabilized R-ALA. Fat-soluble Benfotiamine. No commodity substitutes.
Clinically relevant doses
Doses match or exceed levels used in published trials. No micro-dosing for label decoration.
The formula the research supports.
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